{"id":9999,"date":"2020-02-21T05:33:41","date_gmt":"2020-02-21T08:33:41","guid":{"rendered":"https:\/\/shop.regedent.com\/it\/?post_type=customer_story&#038;p=9969"},"modified":"2021-12-09T12:40:17","modified_gmt":"2021-12-09T15:40:17","slug":"tissue-regenerator","status":"publish","type":"customer_story","link":"https:\/\/shop.regedent.com\/it\/regedent-products\/tissue-regenerator\/","title":{"rendered":"Tissue Regenerator"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Why use hyaluronic acid in dental surgery?<\/h2>\n\n\n\n<p>The gel of <strong>c<span class=\"has-inline-color has-secondary-color\">ross-linked hyaluronic acid (xHyA)<\/span><span class=\"has-inline-color has-dark-color\"> <\/span><\/strong>is used for soft tissue recession surgery, guided tissue regeneration (GTR) as well as guided bone regeneration (GBR). The pharmaceutical-grade cross-linked hyaluronic acid, based gel of non-animal origin is optimized for regenerative peri-implant and periodontal applications.<\/p>\n\n\n\n<ul><li>Accelerated tissue healing &#8211; Coordinates the post-operative inflammation process and accelerates neoangiogenesis. [1,2]<\/li><li>Improved outcome &#8211; Stabilizes coagulum and supports tissue regeneration. [1-4]<\/li><li>Improved predictability &#8211; Bacteriostatic action and reduced pathogen penetration. [5]<\/li><\/ul>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Six reasons to use cross-linked hyaluronic acid in dental surgery:<\/h2>\n\n\n\n<ol><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">Greater outcome predictability<\/span> <\/span>&#8211; xHyA stabilizes blood clot and attracts growth factors to support and accelerate hard and soft tissue formation.[1-4, 17,19]<\/li><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">Faster tissue healing<\/span><\/span> &#8211; xHyA supports angiogenesis [1,10,19] &amp; tissue formation [12,13,15-17] over an extended period. Its special formulation remains present throughout the various phases of the healing process due to its slow degradation pattern (several weeks).[17]<\/li><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">Lower risks of infection<\/span><\/span> &#8211; xHyA\u2019s high molecular weight reduces swelling and discomfort during the healing process.[18,19]<\/li><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">Better patient experience<\/span> <\/span>&#8211; xHyA\u2019s high molecular weight reduces swelling and discomfort during the healing process. [18,19]<\/li><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">Better aesthetics<\/span> <\/span>&#8211; Support scar-less wound healing. [18,19]<\/li><li><span class=\"font-weight-semi-bold\"><span class=\"has-inline-color has-primary-color\">User friendly<\/span><\/span> &#8211; Apply directly on surgical site (in presence of blood), do not rinse. xHyA can be combined with Smartgraft to prepare the \u201esticky bone\u201c in 3 minutes.<\/li><\/ol>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">What does cross-linked hyaluronic acid do?<\/h2>\n\n\n<p>[trp_language language=&#8221;en_US&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Regeneration vs Repair in dental surgery\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/xS-LQ-tpFbc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;it_IT&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Acido ialuronico in chirurgia dentale\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/XzdFA-LesRI?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;fr_FR&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"R\u00e9g\u00e9n\u00e9ration versus R\u00e9paration en chirurgie dentaire\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/46HNFxhQDRU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;de_DE&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Hyalurons\u00e4ure in der Dentalchirurgie\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/xMtRjBmhe4Y?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">The mode of action of hyaluronic acid<\/h3>\n\n\n\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"946\" height=\"651\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=946%2C651&#038;ssl=1\" alt=\"mode of action of surgical-grade cross-linked hyaluronic acid (HA): Hyadent BG\" class=\"wp-image-10277 size-full\" srcset=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?w=946&amp;ssl=1 946w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=600%2C413&amp;ssl=1 600w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=300%2C206&amp;ssl=1 300w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=768%2C529&amp;ssl=1 768w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=16%2C12&amp;ssl=1 16w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=24%2C17&amp;ssl=1 24w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=36%2C25&amp;ssl=1 36w, https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/Capture.jpg?resize=48%2C33&amp;ssl=1 48w\" sizes=\"(max-width: 946px) 100vw, 946px\" data-recalc-dims=\"1\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<ol type=\"1\"><li>Attracts blood<\/li><li>Stabilizes coagulum and supports tissue regeneration<\/li><li>Bacteriostatic effect provides protection<\/li><li>Growth factors attracted by hyaluronic acid<\/li><li>Coordinates inflammation and accelerates angiogenesis<\/li><\/ol>\n<\/div><\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">How to use hyaluronic acid gel?<\/h2>\n\n\n\n<p><strong>Sticky bone in 3 minutes with <span class=\"has-inline-color has-secondary-color\">xHyA <\/span><\/strong><span class=\"has-inline-color has-secondary-color\">gel <\/span><strong>and <span class=\"has-inline-color has-primary-color\">Smart<\/span><span class=\"has-inline-color has-dark-color\">graft<\/span>.<\/strong><\/p>\n\n\n<p>[trp_language language=&#8221;en_US&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Regedent Sticky Bone with cross-linked hyaluronic acid and Smartgraft\" width=\"980\" height=\"551\" src=\"https:\/\/www.youtube.com\/embed\/m2E1SR0V6qo?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;it_IT&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Sticky bone con Smartgraft e l&#039;acido ialuronico de Regedent Italia srl\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/Kf6bRQfNCL8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;fr_FR&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Sticky bone avec Smartgraft et le gel d&#039;acide hyaluronique r\u00e9ticul\u00e9\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/vWur5AGTwu4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;de_DE&#8221;]<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Sticky bone mit Smartgraft und hyalurons\u00e4ure\" width=\"980\" height=\"735\" src=\"https:\/\/www.youtube.com\/embed\/KoBQnmhzZUM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n<p>[\/trp_language]<\/p>\n\n\n\n<p><strong>Deep Miller Class II gingival recession (Prof A Sculean) with cross-linked hyaluronic acid gel<\/strong><\/p>\n\n\n\n<div class=\"fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Baseline\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1.jpg?resize=980%2C591&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1b.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Tunnel\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1b.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1c.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Mobilized Tunnel\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1c.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1d.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Connective tissue graft (CTG)\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1d.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+6<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+8<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1e.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Application of HYADENT BG\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1e.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1g.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Connective tissue graft fixed in the tunnel\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1g.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1h.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Applied HYADENT BG in the tunnel\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1h.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1f.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Application of Hyadent on the connective tissue graft\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1f.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1i.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Laterally closed tunnel\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1i.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1j.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Outcome\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/case-1j.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<p><strong>Infrabony defect (Prof A Pilloni) with a <span class=\"has-inline-color has-secondary-color\">cross-linked hyaluronic acid gel<\/span><\/strong><\/p>\n\n\n\n<div class=\"fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/OPG-pre-OP.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Deep infrabony defect\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/OPG-pre-OP.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-28-01.58.16.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Defect site was opened and cleaned. HYADENT BG was applied directly on the root surface allowing the stabilization of the clot.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-28-01.58.16.jpg?resize=980%2C651&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-28-02.06.02.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"The defect was filled with bone graft material and covered with HYADENT BG\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-28-02.06.02.jpg?resize=980%2C651&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-29-01.48.37.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"72 hours post-operative. Thanks to accelerated wound healing, the wound was closed at this early stage.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/2007-06-29-01.48.37.jpg?resize=980%2C651&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+1<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+3<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/OPG-post-OP.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Radiographical analysis of the site 12 months after treatment shows solid bone structures and a closure of the infrabony defect.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/OPG-post-OP.jpg?resize=980%2C740&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<p><strong>GBR prior to implant placement (Prof D Bozic) with <span class=\"has-inline-color has-secondary-color\">cross-linked hyaluronic acid gel<\/span><span class=\"has-inline-color has-dark-color\"> <\/span>and <a aria-label=\"Smartbrane  (opens in a new tab)\" class=\"rank-math-link\" href=\"https:\/\/shop.regedent.com\/it\/regedent-products\/membranes\/\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"has-inline-color has-primary-color\">Smart<\/span><span class=\"has-inline-color has-dark-color\">brane<\/span> <\/a><\/strong><\/p>\n\n\n\n<div class=\"fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/01.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #1\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/01.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/02.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #2\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/02.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/03.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #3\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/03.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/04.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #4\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/04.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+7<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+9<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/05.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #5\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/05.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/06.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #6\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/06.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/07.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #7\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/07.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/08.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #8\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/08.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/09.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #9\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/09.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/10_6-month.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #10\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/10_6-month.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/11_6-month.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Front in frames - image #11\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/11_6-month.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<p><strong>Pocket sealing after biofilm removal of a case affected by mucositis (Dr M Roncati) <\/strong><\/p>\n\n\n\n<div class=\"fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/1_5-mm-probing-depths-.png\" data-fancybox=\"fancyboxGallery6\" data-caption=\"5 mm probing depths \" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/1_5-mm-probing-depths-.png?resize=980%2C501&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/3_54-Initially-the-clinician-applies-an-innovative-topical-antiseptic-.png?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"An effective Biofilm Eraser\n(PERISOLV\u00ae) is applied.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/3_54-Initially-the-clinician-applies-an-innovative-topical-antiseptic-.png?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/5_After-the-antiseptic-product-has-.png?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"After application of PERISOLV\u00ae and\na reaction time of 30 seconds, the\nbiofilm is mechanically removed\nwith a titanium coated stainless\nsteel curette, mainly with horizontal\nstrokes.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/5_After-the-antiseptic-product-has-.png?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/10_Polishing-with-fluoride-free-prophy-1.png\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Injection of Hyadent BG into the peri-implant pocket\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/10_Polishing-with-fluoride-free-prophy-1.png?resize=980%2C484&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+1<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+3<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/16_At-the-first-professional-hygiene-appointment.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"The healing process is supported by the presence of hyaluronic acid, which has been shown to protect the site and up-regulate several growth factors.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/16_At-the-first-professional-hygiene-appointment.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<p><strong>Soft tissue augmentation with <span class=\"has-inline-color has-secondary-color\">cross-linked hyaluronic acid gel<\/span><span class=\"has-inline-color has-dark-color\"> <\/span>and <span class=\"has-inline-color has-primary-color\">Smart<\/span><span class=\"has-inline-color has-dark-color\">brane<\/span> (Dr M Pierchalla)<\/strong> <\/p>\n\n\n\n<div class=\"fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_1.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Baseline\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_1.jpg?w=980&#038;ssl=1\" alt=\"Post-op\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_2.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Surgery\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_2.jpg?w=980&#038;ssl=1\" alt=\"Surgery\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5 d-none d-sm-inline-block\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_3.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Smartbrane coated with Hyadent BG\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_3.jpg?w=980&#038;ssl=1\" alt=\"Smartbrane coated with Hyadent BG\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-3 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_4_.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Folded coated Smartbrane\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_4_.jpg?w=980&#038;ssl=1\" alt=\"Folded coated Smartbrane\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+4<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+6<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_7.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"9 mth post-op vs baseline\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_7.jpg?w=980&#038;ssl=1\" alt=\"Cross-section 9m vs. baseline\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_8.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"9 months post-op vs basline\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_8.jpg?w=980&#038;ssl=1\" alt=\"9m post-OP vs. baseline\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_6_.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"9 months post-op\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_6_.jpg?w=980&#038;ssl=1\" alt=\"image\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_6.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"9 months post-op\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Pierchalla_6.jpg?w=980&#038;ssl=1\" alt=\"9 months post-op\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">How does pharmaceutical-grade cross-linked hyaluronic acid work?<\/h2>\n\n\n\n<p>The cross-linked hyaluronic acid gel is designed specifically for application in the field of dental surgery. xHyA, as one of the main components of the extracellular matrix, is naturally present in the human body [6-8]. Studies have shown that the prolonged presence of xHyA during the healing process promotes healing by regeneration rather than reparation [9,10]. &nbsp;Besides accelerating the healing of soft tissue and bone[11-13], the bacteriostatic properties of xHyA also protect the wound [5].<\/p>\n\n\n\n<p>Cross-linked hyaluronic acid remains present throughout the various phases of the healing process due to its slow degradation pattern (several weeks) [14]. In addition, it aids the surgical periodontal treatment after application to the root surface and soft tissue. This leads to faster wound closure, substantial pocket reduction, and enhanced attachment [1,3-4]. When mixed with bone substitute material, such as <a aria-label=\"Smartgraft (opens in a new tab)\" class=\"rank-math-link\" href=\"https:\/\/shop.regedent.com\/it\/regedent-products\/porcine-bone-graft\/\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"has-inline-color has-primary-color\"><strong>Smart<\/strong><\/span><span class=\"has-inline-color has-dark-color\"><strong>graft<\/strong><\/span><\/a>,  it<strong><span class=\"has-inline-color has-dark-color\"> <\/span><\/strong>forms an easily manageable putty, which may, in addition, lead to accelerated bone formation [15,16] and reduced swelling and pain. [18,19] <\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer dn\"><\/div>\n\n\n\n<h2 class=\"dn wp-block-heading\">What is <span class=\"has-inline-color has-secondary-color\"><strong>Hyadent <\/strong><\/span><strong>BG<\/strong>?<\/h2>\n\n\n\n<div class=\"dn fgb-gallery-grid\"><div class=\"row mx-gutters-2 mb-6\"><div class=\"col-sm-6 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Regedent-166_white_shadow-scaled.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Conserve at room temperature\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/Regedent-166_white_shadow.jpg?resize=980%2C652&#038;ssl=1\" alt=\"Conserve at room temperature\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"u-media-viewer__icon\"><span class=\"fas fa-plus u-media-viewer__icon-inner\"><\/span><\/span><\/span><\/a><\/div><div class=\"col-sm-6 image-width-class col-5\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/EDP-KG_HyadentBG_3086-scaled2-scaled.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"2 x 1.2ml ampulla of cross-linked hyaluronic acid\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/EDP-KG_HyadentBG_3086-scaled2-scaled.jpg?resize=980%2C655&#038;ssl=1\" alt=\"2 x 1.2ml ampulla of cross-linked hyaluronic acid\" data-recalc-dims=\"1\" \/><span class=\"u-media-viewer__container\"><span class=\"d-none d-sm-inline-block u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+4<\/span><\/span><span class=\"d-sm-none u-media-viewer__icon u-media-viewer__icon--active\"><span class=\"u-media-viewer__icon-inner font-weight-medium\">+4<\/span><\/span><\/span><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/FOTOGRAFICA_03_Hyadent-Bone_Regedent_FTA1560_Druck.jpg?w=980&#038;ssl=1\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Sticky bone mix of Hyadent BG and Smartgraft using a spatula.\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/01\/FOTOGRAFICA_03_Hyadent-Bone_Regedent_FTA1560_Druck.jpg?w=980&#038;ssl=1\" alt=\"Sticky bone mix of Hyadent BG and Smartgraft using a spatula.\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/C6-scaled.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Sealing and healing of the pockets with cross-linked hyaluronic acid.  \" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2020\/02\/C6.jpg?resize=980%2C638&#038;ssl=1\" alt=\"Sealing and healing of the pockets with cross-linked hyaluronic acid.  \" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/03\/smartbrane-preservation-by-hyadent-bg.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Cross-linked hyaluronic acid extends Smartbrane barrier effect beyond 12 weeks\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/03\/smartbrane-preservation-by-hyadent-bg.jpg?resize=980%2C669&#038;ssl=1\" alt=\"Cross-linked hyaluronic acid extends Smartbrane barrier effect beyond 12 weeks\" data-recalc-dims=\"1\" \/><\/a><\/div><div class=\"d-none\"><a class=\"js-fancybox u-media-viewer\" href=\";\" data-src=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/04\/Hard-Tissue_1920x900.jpg\" data-fancybox=\"fancyboxGallery6\" data-caption=\"Cementum and PDL regeneration in infrabony defect with Hyadent BG\" data-speed=\"700\" data-is-infinite=\"true\"><img decoding=\"async\" class=\"img-fluid rounded\" src=\"https:\/\/i0.wp.com\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/04\/Hard-Tissue_1920x900.jpg?resize=980%2C459&#038;ssl=1\" alt=\"Cementum and PDL regeneration in infrabony defect with Hyadent BG\" data-recalc-dims=\"1\" \/><\/a><\/div><\/div><\/div>\n\n\n\n<ul class=\"dn\"><li>Cross-linked hyaluronic acid gel (class III)<\/li><li>Cartridge.of non-animal origin<\/li><li>2 x 1,2 ml ampulla <\/li><li>Store at room temperature (2 \u00b0C \u2013 25 \u00b0C).<\/li><\/ul>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<p>[trp_language language=&#8221;en_US&#8221;]<\/p>\n\n\n\n<div class=\"wp-block-fgb-button fgb-button-wrapper\"><a href=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/11\/202106_HYADENT-BG_EN_DINA4_Web_compressed.pdf\" class=\"fgb-button btn fgb-button--align-center btn-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Download brochure<\/div><\/a><a href=\"https:\/\/ifu.regedent.com\/\" class=\"fgb-button btn fgb-button--align-center btn-outline-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Instruction for Use<\/div><\/a><\/div>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;fr_FR&#8221;]<\/p>\n\n\n\n<div class=\"wp-block-fgb-button fgb-button-wrapper\"><a href=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/11\/202106_HYADENT-BG_EN_DINA4_Web_compressed.pdf\" class=\"fgb-button btn fgb-button--align-center btn-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Download brochure<\/div><\/a><a href=\"https:\/\/ifu.regedent.com\/\" class=\"fgb-button btn fgb-button--align-center btn-outline-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Instruction for Use<\/div><\/a><\/div>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;it_IT&#8221;]<\/p>\n\n\n\n<div class=\"wp-block-fgb-button fgb-button-wrapper\"><a href=\"https:\/\/drive.google.com\/file\/d\/1BRA295whOz8Zp9wtgUfcpQEs6RnTmzNM\/view?usp=sharing\" class=\"fgb-button btn fgb-button--align-center btn-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Download brochure<\/div><\/a><a href=\"https:\/\/ifu.regedent.com\/\" class=\"fgb-button btn fgb-button--align-center btn-outline-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Instruction for Use<\/div><\/a><\/div>\n\n\n<p>[\/trp_language]<\/p>\n\n\n<p>[trp_language language=&#8221;de_DE&#8221;]<\/p>\n\n\n\n<div class=\"wp-block-fgb-button fgb-button-wrapper\"><a href=\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/11\/202106_HYADENT-BG_EN_DINA4_Web_compressed.pdf\" class=\"fgb-button btn fgb-button--align-center btn-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Download brochure<\/div><\/a><a href=\"https:\/\/ifu.regedent.com\/\" class=\"fgb-button btn fgb-button--align-center btn-outline-primary transition-3d-hover\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"fgb-button--inner\">Instruction for Use<\/div><\/a><\/div>\n\n\n<p>[\/trp_language]<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Literature<\/h2>\n\n\n\n<ol><li>King SR, Hickerson WL, Proctor KG. Beneficial actions of exogenous hyaluronic acid on healing. Surgery 1991;109(1):76-84 <\/li><li>Kessiena L. Aya et al. \u2018Hyaluronan in wound healing: Rediscovering a major player.\u2019 Wound Rep Reg 2014;22:579-593. Dental Journal. (2017) Vol.42:104-<\/li><li>Fawzy ES. et al. Local application of hyaluronan gel in conjunction with periodontal surgery: a randomized controlled trial. Clin Oral Invest 2012;16:1229-1236 <\/li><li>Briguglio, F. et al. Treatment of infrabony periodontal defects using a resorbable biopolymer of hyaluronic acid: A randomized clinical trial. Quintessence Int 2013;44:231-240 <\/li><li>Pirnazar P. et al. \u2019Bacteriostatic effects of hyaluronic acid.\u2019 Journal of Periodontology 1999;70:370-374 <\/li><li>Lee JY, Spicer AP. \u2018Hyaluronan: a multifunctional, megadalton, stealth molecule.\u2019 Curr Opin Cell Biol 2000;12:581\u2013586.<\/li><li>McDonald J, Hascall VC. \u2018Hyaluronan mini review series.\u2019 JBiol Chem 2002; 277:4575\u20134579.<\/li><li>Jiang D et al. \u2018Hyaluronan as an immune regulator in human diseases.\u2019 Physiol Rev 2011;91:221\u2013264.<\/li><li>Longaker T et al. \u2018Studies in Fetal Wound Healing: V. A prolonged presence of hyaluronic acid characterizes fetal wound healing\u2019 Ann. Surg. 1991; April:292\u2013296.<\/li><li>Mast BA et al. \u2018Hyaluronic Acid Modulates Proliferation, Collagen and Protein Synthesis of Cultured Fetal Fibroblast\u2019 Matrix, 1993;13:441\u2013446.<\/li><li>Salbach J et al. \u2018Regenerative potential of glycosaminoglycans for skin and bone.\u2019 J Mol Med 2012;90:625\u2013635.<\/li><li>Muzaffer A. et al. \u2018The Effect of Hyaluronic Acid-supplemented Bone Graft in Bone Healing: Experimental Study in Rabbits \u2019 J Biomater Appl 2006 20:209<\/li><li>Sasaki T, Watanabe C, Bone. Vol. 16. No.1 January 1995:9-15<\/li><li>De Boulle K, Glogau R, Kono T, et al. \u201aA Review of the Metabolism of 1,4-Butanediol Diglycidyl Ether\u2013 Crosslinked Hyaluronic Acid Dermal Fillers.\u2019 Dermatologic Surgery 2013;39(12):1758-1766<\/li><li>Stiller M. et al. \u2018Performance of \u03b2-tricalcium phosphate granules and putty, bone grafting materials after bilateral sinus floor augmentation in humans\u2019 Biomaterials 2014;35(10):3154-3163.<\/li><li>Mendes RM et al. \u2018Sodium hyaluronate accelerates the healing process in tooth sockets of rat\u2019Arch Oral Biol 2008; 53:1155\u20131162<\/li><li>Shirakata Y, Imafuji T, Nakamura T, Kawakami Y, Shinohara Y, Noguchi K, Pilloni A, Sculean A. Periodontal wound healing\/regeneration of two-wall intrabony defects following reconstructive surgery with cross-linked hyaluronic acid-gel with or without a collagen matrix: a preclinical study in dogs. Quintessence Int. 2021;0(0):308-316. <a href=\"10.3290\/j.qi.b937003.\" target=\"_blank\" rel=\"noreferrer noopener\">doi: 10.3290\/j.qi.b937003. <\/a><\/li><li> Y\u0131ld\u0131r\u0131m S, \u00d6zener H\u00d6, Do\u011fan B, Kuru B. Effect of topically applied hyaluronic acid on pain and palatal epithelial wound healing: An examiner-masked, randomized, controlled clinical trial. J Periodontol. 2018;89(1):36-45. doi:10.1902\/jop.2017.170105<\/li><li>Pilloni A, Schmdlin PR, Sahrmann P, Sculean A, Rojas MA. \u2018Effectiveness of adjunctive hyaluronic acid application in coronally advanced flap in Miller class I single gingival recession sites: a randomized controlled clinical trial, Clinical Oral Investigations, 2019 https:\/\/doi.org\/10.1007\/s00784-018-2537-4<\/li><\/ol>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dental regeneration for soft and hard tissues<\/p>\n","protected":false},"author":1,"featured_media":10447,"template":"","meta":{"_featured_logo":"{\"id\":11437,\"url\":\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/2021\/06\/image-13.png\"}","_additional_information_count":4,"_key_features_count":1,"_custom_static_content_id":10005,"_additional_information":"{\"label1\":\"Product\",\"value1\":\"Biologics\",\"label2\":\"Size\",\"value2\":\"2 x 1,2ml\",\"label3\":\"Composition\",\"value3\":\"1.6% cross-linked hyaluronic acid (xHyA), 0.2% natural hyaluronic acid (HyA)\",\"label4\":\"\",\"value4\":\"\"}","_key_features":"{\"imageID1\":\"\",\"imageUrl1\":\"\",\"title1\":\"\",\"description1\":\"\",\"title2\":\"Amazon Fire TV\",\"description2\":\"Amazon Fire TV is a digital media player and its microconsole remote.\",\"imageID2\":10014,\"imageUrl2\":\"https:\/\/shop.regedent.com\/it\/wp-content\/uploads\/sites\/54\/2020\/02\/customer-svg-2.png\"}"},"_links":{"self":[{"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/customer_story\/9999"}],"collection":[{"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/customer_story"}],"about":[{"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/types\/customer_story"}],"author":[{"embeddable":true,"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":68,"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/customer_story\/9999\/revisions"}],"predecessor-version":[{"id":12207,"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/customer_story\/9999\/revisions\/12207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/media\/10447"}],"wp:attachment":[{"href":"https:\/\/shop.regedent.com\/it\/wp-json\/wp\/v2\/media?parent=9999"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}